Injectable Solution of Ciprofloxacin 400mg/100ml
Trade Name: Parsacip 400
Generic Name: Ciprofloxacin

Dosage Form and Packaging:
A clear, colorless to light yellow injectable solution, supplied in 100 ml glass bottles for intravenous infusion.

Drug Classification:
Antibiotic from the Fluoroquinolone group.

Indications:
Ciprofloxacin is used for the treatment of various bacterial infections, including:

• Respiratory tract infections (bronchitis, pneumonia)
• Urinary tract infections
• Skin and soft tissue infections
• Gastrointestinal infections
• Sepsis
• Bone and joint infections
• Intra-abdominal infections (in combination with Metronidazole).

Dosage and Administration:

• Adults: 400 mg every 12 hours via slow intravenous infusion over 60 minutes.
• Children: 10–20 mg/kg body weight every 12 hours (up to a maximum of 400 mg per day).
  The dose may vary depending on the type and severity of infection and kidney/liver function.

Contraindications:

• Hypersensitivity to Ciprofloxacin or other Fluoroquinolones.
• Children and adolescents during growth (except in special cases).
• Patients with a history of seizures or CNS disorders.
• Pregnancy and lactation (unless advised by a doctor).

Precautions:

• Monitor kidney function during treatment.
• Avoid direct exposure to sunlight.
• Use cautiously with anticonvulsants, anti-inflammatory drugs, and theophylline.
• In case of severe diarrhea, discontinue treatment and consult a doctor (possible Clostridium difficile colitis).

Drug Interactions:

• Theophylline, Cyclosporine, Oral anticoagulants, Antiarrhythmic drugs (may increase risk of QT prolongation).

Possible Side Effects:

• Nausea, vomiting, diarrhea, headache, dizziness, photosensitivity, sleep disturbances, elevated liver enzymes.
• Rarely: seizures, severe allergic reactions (anaphylactoid reactions).

Storage Conditions:
Store below 25°C, protected from light and freezing.
Do not use after the expiration date.

Supply Conditions:
To be dispensed only by prescription.

Manufacturer Address:
Parsaava Injectable Solutions Manufacturing Factory
Industrial City, Phase 3, Sosan 5, Herat, Afghanistan